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Date: 2008-12-05 Place: Biology Lecture Hall, Biology Building, LU Sölvegatan 35, Lund Abstract: Since the importance of molecular structure and dynamics for the understanding of biological activity was established decades ago, there has not appeared a single biophysical method that on its own would the information that is needed: the mean structural organization and motions around it of the atoms in these molecules, in their cellular environment, and how they change during their functional interactions. Complementarity should be the operational keyword when experimental methods in molecular biophysics are discussed. Each method, with its strengths and weaknesses, provides partial information which not accessible by others; the deepest understanding is achieved by combining all the available information. By using examples of recent work on macromolecular assemblies, membranes and in-situ studies in live cells, I shall discuss the information that can be obtained from electron microscopy, X-ray and neutron scattering and NMR, and discuss perspective developments in these methods. Download PowerPoint presentation:
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Speaker: Giuseppe Zaccai, Institut Laue Langevin, Grenoble, France